Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1.
Identifieur interne : 000146 ( Main/Exploration ); précédent : 000145; suivant : 000147Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1.
Auteurs : Daniel Lüdke [Allemagne] ; Charlotte Roth [Allemagne] ; Sieglinde A. Kamrad [Allemagne] ; Jana Messerschmidt [Allemagne] ; Denise Hartken [Allemagne] ; Jonas Appel [Allemagne] ; Bojan F. Hörnich [Allemagne] ; Qiqi Yan [Allemagne] ; Stefan Kusch [Allemagne] ; Melanie Klenke [Allemagne] ; Annette Gunkel [Allemagne] ; Lennart Wirthmueller [Allemagne] ; Marcel Wiermer [Allemagne]Source :
- The Plant journal : for cell and molecular biology [ 1365-313X ] ; 2020.
Abstract
IMPORTIN-α3/MOS6 (MODIFIER OF SNC1, 6) is one of nine importin-α isoforms in Arabidopsis that recruit nuclear localization signal (NLS)-containing cargo proteins to the nuclear import machinery. IMP-α3/MOS6 is required genetically for full autoimmunity of the nucleotide-binding leucine-rich repeat (NLR) immune receptor mutant snc1 (suppressor of npr1-1, constitutive 1) and MOS6 also contributes to basal disease resistance. Here, we investigated the contribution of the other importin-α genes to both types of immune responses, and we analyzed potential interactions of all importin-α isoforms with SNC1. By using reverse-genetic analyses in Arabidopsis and protein-protein interaction assays in N. benthamiana we provide evidence that among the nine α-importins in Arabidopsis, IMP-α3/MOS6 is the main nuclear transport receptor of SNC1, and that IMP-α3/MOS6 is required selectively for autoimmunity of snc1 and basal resistance to mildly virulent Pseudomonas syringae in Arabidopsis.
DOI: 10.1111/tpj.15082
PubMed: 33210758
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wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Roth, Charlotte" sort="Roth, Charlotte" uniqKey="Roth C" first="Charlotte" last="Roth">Charlotte Roth</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Kamrad, Sieglinde A" sort="Kamrad, Sieglinde A" uniqKey="Kamrad S" first="Sieglinde A" last="Kamrad">Sieglinde A. Kamrad</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Messerschmidt, Jana" sort="Messerschmidt, Jana" uniqKey="Messerschmidt J" first="Jana" last="Messerschmidt">Jana Messerschmidt</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Hartken, Denise" sort="Hartken, Denise" uniqKey="Hartken D" first="Denise" last="Hartken">Denise Hartken</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Appel, Jonas" sort="Appel, Jonas" uniqKey="Appel J" first="Jonas" last="Appel">Jonas Appel</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Hornich, Bojan F" sort="Hornich, Bojan F" uniqKey="Hornich B" first="Bojan F" last="Hörnich">Bojan F. Hörnich</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Yan, Qiqi" sort="Yan, Qiqi" uniqKey="Yan Q" first="Qiqi" last="Yan">Qiqi Yan</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Kusch, Stefan" sort="Kusch, Stefan" uniqKey="Kusch S" first="Stefan" last="Kusch">Stefan Kusch</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Klenke, Melanie" sort="Klenke, Melanie" uniqKey="Klenke M" first="Melanie" last="Klenke">Melanie Klenke</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Gunkel, Annette" sort="Gunkel, Annette" uniqKey="Gunkel A" first="Annette" last="Gunkel">Annette Gunkel</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Wirthmueller, Lennart" sort="Wirthmueller, Lennart" uniqKey="Wirthmueller L" first="Lennart" last="Wirthmueller">Lennart Wirthmueller</name><affiliation wicri:level="1"><nlm:affiliation>Biochemistry of Plant Interactions, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Saale, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Biochemistry of Plant Interactions, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Saale</wicri:regionArea><wicri:noRegion>Saale</wicri:noRegion><wicri:noRegion>Saale</wicri:noRegion><wicri:noRegion>Saale</wicri:noRegion></affiliation></author><author><name sortKey="Wiermer, Marcel" sort="Wiermer, Marcel" uniqKey="Wiermer M" first="Marcel" last="Wiermer">Marcel Wiermer</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Goettingen Center for Molecular Biosciences (GZMB), University of Goettingen, 37077, Goettingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Plant-Microbe Interactions Research Group, Goettingen Center for Molecular Biosciences (GZMB), University of Goettingen, 37077, Goettingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author></analytic><series><title level="j">The Plant journal : for cell and molecular biology</title><idno type="eISSN">1365-313X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">IMPORTIN-α3/MOS6 (MODIFIER OF SNC1, 6) is one of nine importin-α isoforms in Arabidopsis that recruit nuclear localization signal (NLS)-containing cargo proteins to the nuclear import machinery. IMP-α3/MOS6 is required genetically for full autoimmunity of the nucleotide-binding leucine-rich repeat (NLR) immune receptor mutant snc1 (suppressor of npr1-1, constitutive 1) and MOS6 also contributes to basal disease resistance. Here, we investigated the contribution of the other importin-α genes to both types of immune responses, and we analyzed potential interactions of all importin-α isoforms with SNC1. By using reverse-genetic analyses in Arabidopsis and protein-protein interaction assays in N. benthamiana we provide evidence that among the nine α-importins in Arabidopsis, IMP-α3/MOS6 is the main nuclear transport receptor of SNC1, and that IMP-α3/MOS6 is required selectively for autoimmunity of snc1 and basal resistance to mildly virulent Pseudomonas syringae in Arabidopsis.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33210758</PMID><DateRevised><Year>2020</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-313X</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Nov</Month><Day>19</Day></PubDate></JournalIssue><Title>The Plant journal : for cell and molecular biology</Title><ISOAbbreviation>Plant J</ISOAbbreviation></Journal><ArticleTitle>Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1111/tpj.15082</ELocationID><Abstract><AbstractText>IMPORTIN-α3/MOS6 (MODIFIER OF SNC1, 6) is one of nine importin-α isoforms in Arabidopsis that recruit nuclear localization signal (NLS)-containing cargo proteins to the nuclear import machinery. IMP-α3/MOS6 is required genetically for full autoimmunity of the nucleotide-binding leucine-rich repeat (NLR) immune receptor mutant snc1 (suppressor of npr1-1, constitutive 1) and MOS6 also contributes to basal disease resistance. Here, we investigated the contribution of the other importin-α genes to both types of immune responses, and we analyzed potential interactions of all importin-α isoforms with SNC1. By using reverse-genetic analyses in Arabidopsis and protein-protein interaction assays in N. benthamiana we provide evidence that among the nine α-importins in Arabidopsis, IMP-α3/MOS6 is the main nuclear transport receptor of SNC1, and that IMP-α3/MOS6 is required selectively for autoimmunity of snc1 and basal resistance to mildly virulent Pseudomonas syringae in Arabidopsis.</AbstractText><CopyrightInformation>This article is protected by copyright. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lüdke</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roth</LastName><ForeName>Charlotte</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kamrad</LastName><ForeName>Sieglinde A</ForeName><Initials>SA</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Messerschmidt</LastName><ForeName>Jana</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hartken</LastName><ForeName>Denise</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Appel</LastName><ForeName>Jonas</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hörnich</LastName><ForeName>Bojan F</ForeName><Initials>BF</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yan</LastName><ForeName>Qiqi</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kusch</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Klenke</LastName><ForeName>Melanie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gunkel</LastName><ForeName>Annette</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wirthmueller</LastName><ForeName>Lennart</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Biochemistry of Plant Interactions, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Saale, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wiermer</LastName><ForeName>Marcel</ForeName><Initials>M</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-1232-2707</Identifier><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Institute for Plant Sciences, University of Goettingen, Albrecht-von-Haller, Julia-Lermontowa-Weg 3, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Molecular Biology of Plant-Microbe Interactions Research Group, Goettingen Center for Molecular Biosciences (GZMB), University of Goettingen, 37077, Goettingen, Germany.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>11</Month><Day>19</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Plant J</MedlineTA><NlmUniqueID>9207397</NlmUniqueID><ISSNLinking>0960-7412</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Arabidopsis
</Keyword><Keyword MajorTopicYN="N">IMPORTIN-α</Keyword><Keyword MajorTopicYN="N">NLR</Keyword><Keyword MajorTopicYN="N">SNC1</Keyword><Keyword MajorTopicYN="N">nuclear import</Keyword><Keyword MajorTopicYN="N">plant immunity</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>11</Month><Day>19</Day><Hour>8</Hour><Minute>47</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>11</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>11</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33210758</ArticleId><ArticleId IdType="doi">10.1111/tpj.15082</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country><region><li>Basse-Saxe</li></region><settlement><li>Göttingen</li></settlement></list><tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Ludke, Daniel" sort="Ludke, Daniel" uniqKey="Ludke D" first="Daniel" last="Lüdke">Daniel Lüdke</name></region><name sortKey="Appel, Jonas" sort="Appel, Jonas" uniqKey="Appel J" first="Jonas" last="Appel">Jonas Appel</name><name sortKey="Gunkel, Annette" sort="Gunkel, Annette" uniqKey="Gunkel A" first="Annette" last="Gunkel">Annette Gunkel</name><name sortKey="Hartken, Denise" sort="Hartken, Denise" uniqKey="Hartken D" first="Denise" last="Hartken">Denise Hartken</name><name sortKey="Hornich, Bojan F" sort="Hornich, Bojan F" uniqKey="Hornich B" first="Bojan F" last="Hörnich">Bojan F. Hörnich</name><name sortKey="Kamrad, Sieglinde A" sort="Kamrad, Sieglinde A" uniqKey="Kamrad S" first="Sieglinde A" last="Kamrad">Sieglinde A. Kamrad</name><name sortKey="Klenke, Melanie" sort="Klenke, Melanie" uniqKey="Klenke M" first="Melanie" last="Klenke">Melanie Klenke</name><name sortKey="Kusch, Stefan" sort="Kusch, Stefan" uniqKey="Kusch S" first="Stefan" last="Kusch">Stefan Kusch</name><name sortKey="Messerschmidt, Jana" sort="Messerschmidt, Jana" uniqKey="Messerschmidt J" first="Jana" last="Messerschmidt">Jana Messerschmidt</name><name sortKey="Roth, Charlotte" sort="Roth, Charlotte" uniqKey="Roth C" first="Charlotte" last="Roth">Charlotte Roth</name><name sortKey="Wiermer, Marcel" sort="Wiermer, Marcel" uniqKey="Wiermer M" first="Marcel" last="Wiermer">Marcel Wiermer</name><name sortKey="Wiermer, Marcel" sort="Wiermer, Marcel" uniqKey="Wiermer M" first="Marcel" last="Wiermer">Marcel Wiermer</name><name sortKey="Wirthmueller, Lennart" sort="Wirthmueller, Lennart" uniqKey="Wirthmueller L" first="Lennart" last="Wirthmueller">Lennart Wirthmueller</name><name sortKey="Yan, Qiqi" sort="Yan, Qiqi" uniqKey="Yan Q" first="Qiqi" last="Yan">Qiqi Yan</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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